Infectious diseases

Infectious Diseases span a wide range of possible organisms, from viruses to bacteria to parasites and fungi – all tiny organisms that can do us harm.

They all require proteins at some point in their life cycle to ensure survival (and thus continued disease), and we research how specific known proteins important in these disorders can be disrupted. For example in viruses, common target proteins for disruption are the proteases, which help cut proteins in correct functional sizes, and polymerases, which replicate and convert genetic material for new copies of the organism. In each of the diseases listed below, we’re attempting to understand these proteins and find strategies to disrupt them.

By CDC/Cynthia Goldsmith [Public domain], via Wikimedia Commons
By CDC/Cynthia Goldsmith [Public domain], via Wikimedia Commons